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Role of tumor necrosis factor–α and its receptors in diesel exhaust particle-induced pulmonary inflammation

Inhalation of diesel exhaust particles (DEP) induces an inflammatory reaction in the lung. However, the underlying mechanisms remain to be elucidated. Tumor necrosis factor alpha (TNF-α) is a pro-inflammatory cytokine that operates by binding to tumor necrosis factor receptor 1 (TNFR1) and tumor nec...

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Detalles Bibliográficos
Autores principales: Kumar, Smitha, Joos, Guy, Boon, Louis, Tournoy, Kurt, Provoost, Sharen, Maes, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599628/
https://www.ncbi.nlm.nih.gov/pubmed/28912506
http://dx.doi.org/10.1038/s41598-017-11991-7