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Deconvolution of DNA methylation identifies differentially methylated gene regions on 1p36 across breast cancer subtypes

Breast cancer is a complex disease consisting of four distinct molecular subtypes. DNA methylation-based (DNAm) studies in tumors are complicated further by disease heterogeneity. In the present study, we compared DNAm in breast tumors with normal-adjacent breast samples from The Cancer Genome Atlas...

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Detalles Bibliográficos
Autores principales: Titus, Alexander J., Way, Gregory P., Johnson, Kevin C., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599639/
https://www.ncbi.nlm.nih.gov/pubmed/28912426
http://dx.doi.org/10.1038/s41598-017-10199-z