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Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis

Esophageal mucosal calcinosis (EMC) is a rare cause of dysphagia with high morbidity. We present a patient who experienced melena and 3 months of solid and liquid dysphagia along with bilateral lower extremity pain, erythema, and edema later determined to be calcific uremic arteriolopathy (CUA), or...

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Detalles Bibliográficos
Autores principales: Garber, Ari, Arora, Zubin, Welch, Nicole, Lapinski, James, Burke, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599692/
https://www.ncbi.nlm.nih.gov/pubmed/28932755
http://dx.doi.org/10.14309/crj.2017.108
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author Garber, Ari
Arora, Zubin
Welch, Nicole
Lapinski, James
Burke, Carol A.
author_facet Garber, Ari
Arora, Zubin
Welch, Nicole
Lapinski, James
Burke, Carol A.
author_sort Garber, Ari
collection PubMed
description Esophageal mucosal calcinosis (EMC) is a rare cause of dysphagia with high morbidity. We present a patient who experienced melena and 3 months of solid and liquid dysphagia along with bilateral lower extremity pain, erythema, and edema later determined to be calcific uremic arteriolopathy (CUA), or calciphylaxis. An esophagogastroduodenoscopy revealed nodularity and linear ulcerations in the upper third of the esophagus. Histology showed active inflammation and ulceration with small foci of subepithelial and intraepithelial calcification consistent with EMC. There is no known treatment for this disorder. Sodium thiosulfate, typically used to treat CUA, did not improve her dysphagia.
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spelling pubmed-55996922017-09-20 Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis Garber, Ari Arora, Zubin Welch, Nicole Lapinski, James Burke, Carol A. ACG Case Rep J Case Report Esophageal mucosal calcinosis (EMC) is a rare cause of dysphagia with high morbidity. We present a patient who experienced melena and 3 months of solid and liquid dysphagia along with bilateral lower extremity pain, erythema, and edema later determined to be calcific uremic arteriolopathy (CUA), or calciphylaxis. An esophagogastroduodenoscopy revealed nodularity and linear ulcerations in the upper third of the esophagus. Histology showed active inflammation and ulceration with small foci of subepithelial and intraepithelial calcification consistent with EMC. There is no known treatment for this disorder. Sodium thiosulfate, typically used to treat CUA, did not improve her dysphagia. American College of Gastroenterology 2017-09-13 /pmc/articles/PMC5599692/ /pubmed/28932755 http://dx.doi.org/10.14309/crj.2017.108 Text en Copyright © Garber et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Garber, Ari
Arora, Zubin
Welch, Nicole
Lapinski, James
Burke, Carol A.
Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title_full Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title_fullStr Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title_full_unstemmed Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title_short Extraosseous Calcification of the Esophagus: Clinicopathologic Correlates of Esophageal Mucosal Calcinosis
title_sort extraosseous calcification of the esophagus: clinicopathologic correlates of esophageal mucosal calcinosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599692/
https://www.ncbi.nlm.nih.gov/pubmed/28932755
http://dx.doi.org/10.14309/crj.2017.108
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