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Ionic Current-Based Mapping of Short Sequence Motifs in Single DNA Molecules Using Solid-State Nanopores

[Image: see text] Nanopore sensors show great potential for rapid, single-molecule determination of DNA sequence information. Here, we develop an ionic current-based method for determining the positions of short sequence motifs in double-stranded DNA molecules with solid-state nanopores. Using the D...

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Detalles Bibliográficos
Autores principales: Chen, Kaikai, Juhasz, Matyas, Gularek, Felix, Weinhold, Elmar, Tian, Yu, Keyser, Ulrich F., Bell, Nicholas A. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599873/
https://www.ncbi.nlm.nih.gov/pubmed/28829136
http://dx.doi.org/10.1021/acs.nanolett.7b01009