Genome build information is an essential part of genomic track files

Genomic locations are represented as coordinates on a specific genome build version, but the build information is frequently missing when coordinates are provided. We show that this information is essential to correctly interpret and analyse the genomic intervals contained in genomic track files. Al...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanduri, Chakravarthi, Domanska, Diana, Hovig, Eivind, Sandve, Geir Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Open Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599886/
https://www.ncbi.nlm.nih.gov/pubmed/28911336
http://dx.doi.org/10.1186/s13059-017-1312-1
Descripción
Sumario:Genomic locations are represented as coordinates on a specific genome build version, but the build information is frequently missing when coordinates are provided. We show that this information is essential to correctly interpret and analyse the genomic intervals contained in genomic track files. Although not a substitute for best practices, we also provide a tool to predict the genome build version of genomic track files. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-017-1312-1) contains supplementary material, which is available to authorized users.

Ejemplares similares