IL-12 Influence mTOR to Modulate CD8(+) T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis

Objective: To investigate whether mTOR signaling pathway regulate the proliferation and differentiation of CD8(+) T cells by transcription factors T-bet and Eomes, and explore the role of IL-12 in this biological procedure. Methods: Aspergillus fumigatus spore suspension nasal inhalation was used to...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Li, Jingdong, Han, Qiyang, Yang, Fei, Xiao, Yu, Xiao, Meng, Xu, Yingchun, Su, Longxiang, Cui, Na, Liu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599921/
https://www.ncbi.nlm.nih.gov/pubmed/28924369
http://dx.doi.org/10.7150/ijms.20212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599921/
https://www.ncbi.nlm.nih.gov/pubmed/28924369
http://dx.doi.org/10.7150/ijms.20212

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