Cargando…

The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review

Meta‐analyses combine the results of multiple studies of a common question. Approaches based on effect size estimates from each study are generally regarded as the most informative. However, these methods can only be used if comparable effect sizes can be computed from each study, and this may not b...

Descripción completa

Detalles Bibliográficos
Autores principales: Harrison, Sean, Jones, Hayley E., Martin, Richard M., Lewis, Sarah J., Higgins, Julian P.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599982/
https://www.ncbi.nlm.nih.gov/pubmed/28453179
http://dx.doi.org/10.1002/jrsm.1239
_version_ 1783264161842593792
author Harrison, Sean
Jones, Hayley E.
Martin, Richard M.
Lewis, Sarah J.
Higgins, Julian P.T.
author_facet Harrison, Sean
Jones, Hayley E.
Martin, Richard M.
Lewis, Sarah J.
Higgins, Julian P.T.
author_sort Harrison, Sean
collection PubMed
description Meta‐analyses combine the results of multiple studies of a common question. Approaches based on effect size estimates from each study are generally regarded as the most informative. However, these methods can only be used if comparable effect sizes can be computed from each study, and this may not be the case due to variation in how the studies were done or limitations in how their results were reported. Other methods, such as vote counting, are then used to summarize the results of these studies, but most of these methods are limited in that they do not provide any indication of the magnitude of effect. We propose a novel plot, the albatross plot, which requires only a 1‐sided P value and a total sample size from each study (or equivalently a 2‐sided P value, direction of effect and total sample size). The plot allows an approximate examination of underlying effect sizes and the potential to identify sources of heterogeneity across studies. This is achieved by drawing contours showing the range of effect sizes that might lead to each P value for given sample sizes, under simple study designs. We provide examples of albatross plots using data from previous meta‐analyses, allowing for comparison of results, and an example from when a meta‐analysis was not possible.
format Online
Article
Text
id pubmed-5599982
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-55999822017-10-02 The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review Harrison, Sean Jones, Hayley E. Martin, Richard M. Lewis, Sarah J. Higgins, Julian P.T. Res Synth Methods Original Articles Meta‐analyses combine the results of multiple studies of a common question. Approaches based on effect size estimates from each study are generally regarded as the most informative. However, these methods can only be used if comparable effect sizes can be computed from each study, and this may not be the case due to variation in how the studies were done or limitations in how their results were reported. Other methods, such as vote counting, are then used to summarize the results of these studies, but most of these methods are limited in that they do not provide any indication of the magnitude of effect. We propose a novel plot, the albatross plot, which requires only a 1‐sided P value and a total sample size from each study (or equivalently a 2‐sided P value, direction of effect and total sample size). The plot allows an approximate examination of underlying effect sizes and the potential to identify sources of heterogeneity across studies. This is achieved by drawing contours showing the range of effect sizes that might lead to each P value for given sample sizes, under simple study designs. We provide examples of albatross plots using data from previous meta‐analyses, allowing for comparison of results, and an example from when a meta‐analysis was not possible. John Wiley and Sons Inc. 2017-04-28 2017-09 /pmc/articles/PMC5599982/ /pubmed/28453179 http://dx.doi.org/10.1002/jrsm.1239 Text en Copyright © 2017 The Authors. Research Synthesis Methods Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Harrison, Sean
Jones, Hayley E.
Martin, Richard M.
Lewis, Sarah J.
Higgins, Julian P.T.
The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title_full The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title_fullStr The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title_full_unstemmed The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title_short The albatross plot: A novel graphical tool for presenting results of diversely reported studies in a systematic review
title_sort albatross plot: a novel graphical tool for presenting results of diversely reported studies in a systematic review
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599982/
https://www.ncbi.nlm.nih.gov/pubmed/28453179
http://dx.doi.org/10.1002/jrsm.1239
work_keys_str_mv AT harrisonsean thealbatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT joneshayleye thealbatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT martinrichardm thealbatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT lewissarahj thealbatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT higginsjulianpt thealbatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT harrisonsean albatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT joneshayleye albatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT martinrichardm albatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT lewissarahj albatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview
AT higginsjulianpt albatrossplotanovelgraphicaltoolforpresentingresultsofdiverselyreportedstudiesinasystematicreview