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MR Imaging of Fetuses to Evaluate Placental Insufficiency
PURPOSE: To evaluate morphological and signal intensity (SI) changes of placental insufficiency on magnetic resonance imaging (MRI) and to assess morphological changes and decreased flow voids (FVs) on T(2)-weighted rapid acquisition with relaxation enhancement (RARE) images for diagnosing placental...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Japanese Society for Magnetic Resonance in Medicine
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600058/ https://www.ncbi.nlm.nih.gov/pubmed/26607809 http://dx.doi.org/10.2463/mrms.mp.2015-0051 |
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author | OHGIYA, Yoshimitsu NOBUSAWA, Hiroshi SEINO, Noritaka MIYAGAMI, Osamu YAGI, Naomi HIROTO, Sasamori MUNECHIKA, Jiro HIROSE, Masanori TAKEYAMA, Nobuyuki OHIKE, Nobuyuki MATSUOKA, Ryu SEKIZAWA, Akihiko GOKAN, Takehiko |
author_facet | OHGIYA, Yoshimitsu NOBUSAWA, Hiroshi SEINO, Noritaka MIYAGAMI, Osamu YAGI, Naomi HIROTO, Sasamori MUNECHIKA, Jiro HIROSE, Masanori TAKEYAMA, Nobuyuki OHIKE, Nobuyuki MATSUOKA, Ryu SEKIZAWA, Akihiko GOKAN, Takehiko |
author_sort | OHGIYA, Yoshimitsu |
collection | PubMed |
description | PURPOSE: To evaluate morphological and signal intensity (SI) changes of placental insufficiency on magnetic resonance imaging (MRI) and to assess morphological changes and decreased flow voids (FVs) on T(2)-weighted rapid acquisition with relaxation enhancement (RARE) images for diagnosing placental insufficiency. METHODS: Fifty singleton fetuses underwent MRI using a 1.5-T MR scanner. Placental thickness, area, volume, SI, amniotic fluid SI, and size of FVs between the uterus and the placenta were measured on MR images. Two radiologists reviewed T(2)-weighted RARE images for globular appearance of the placenta and FVs between the uterus and the placenta. Data were analyzed using t-tests, McNemar’s tests, and areas under the receiver operating characteristic curve (AUCs) at 5% level of significance. RESULTS: Twenty-five of the 50 pregnancies were categorized as having an insufficient placenta. Significant differences were observed between insufficient and normal placentas in mean placental thickness, area, volume, placenta to amniotic fluid SI ratio, and size of FVs (49.0 mm vs. 36.9 mm, 1.62 × 10(4) mm(2) vs. 2.67 × 10(4) mm(2), 5.13 × 10(5) mm(3) vs. 6.56 × 10(5) mm(3), 0.549 vs. 0.685, and 3.4 mm vs. 4.3 mm, respectively). The sensitivity and accuracy using globular appearance plus decreased FVs were greater than those using decreased FVs (P < 0.01). There was no significant difference among AUCs using globular appearance and decreased FVs, and globular appearance plus decreased FVs. CONCLUSIONS: Placental insufficiency was associated with placental thickness, area, volume, placenta to amniotic fluid SI ratio, and size of FVs. Evaluating FVs on T(2)-weighted RARE images can be useful for detecting placental insufficiency, particularly in placentas without globular appearance on MR images. |
format | Online Article Text |
id | pubmed-5600058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Japanese Society for Magnetic Resonance in Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-56000582017-10-23 MR Imaging of Fetuses to Evaluate Placental Insufficiency OHGIYA, Yoshimitsu NOBUSAWA, Hiroshi SEINO, Noritaka MIYAGAMI, Osamu YAGI, Naomi HIROTO, Sasamori MUNECHIKA, Jiro HIROSE, Masanori TAKEYAMA, Nobuyuki OHIKE, Nobuyuki MATSUOKA, Ryu SEKIZAWA, Akihiko GOKAN, Takehiko Magn Reson Med Sci Major Paper PURPOSE: To evaluate morphological and signal intensity (SI) changes of placental insufficiency on magnetic resonance imaging (MRI) and to assess morphological changes and decreased flow voids (FVs) on T(2)-weighted rapid acquisition with relaxation enhancement (RARE) images for diagnosing placental insufficiency. METHODS: Fifty singleton fetuses underwent MRI using a 1.5-T MR scanner. Placental thickness, area, volume, SI, amniotic fluid SI, and size of FVs between the uterus and the placenta were measured on MR images. Two radiologists reviewed T(2)-weighted RARE images for globular appearance of the placenta and FVs between the uterus and the placenta. Data were analyzed using t-tests, McNemar’s tests, and areas under the receiver operating characteristic curve (AUCs) at 5% level of significance. RESULTS: Twenty-five of the 50 pregnancies were categorized as having an insufficient placenta. Significant differences were observed between insufficient and normal placentas in mean placental thickness, area, volume, placenta to amniotic fluid SI ratio, and size of FVs (49.0 mm vs. 36.9 mm, 1.62 × 10(4) mm(2) vs. 2.67 × 10(4) mm(2), 5.13 × 10(5) mm(3) vs. 6.56 × 10(5) mm(3), 0.549 vs. 0.685, and 3.4 mm vs. 4.3 mm, respectively). The sensitivity and accuracy using globular appearance plus decreased FVs were greater than those using decreased FVs (P < 0.01). There was no significant difference among AUCs using globular appearance and decreased FVs, and globular appearance plus decreased FVs. CONCLUSIONS: Placental insufficiency was associated with placental thickness, area, volume, placenta to amniotic fluid SI ratio, and size of FVs. Evaluating FVs on T(2)-weighted RARE images can be useful for detecting placental insufficiency, particularly in placentas without globular appearance on MR images. Japanese Society for Magnetic Resonance in Medicine 2015-11-25 /pmc/articles/PMC5600058/ /pubmed/26607809 http://dx.doi.org/10.2463/mrms.mp.2015-0051 Text en © 2015 Japanese Society for Magnetic Resonance in Medicine This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Major Paper OHGIYA, Yoshimitsu NOBUSAWA, Hiroshi SEINO, Noritaka MIYAGAMI, Osamu YAGI, Naomi HIROTO, Sasamori MUNECHIKA, Jiro HIROSE, Masanori TAKEYAMA, Nobuyuki OHIKE, Nobuyuki MATSUOKA, Ryu SEKIZAWA, Akihiko GOKAN, Takehiko MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title | MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title_full | MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title_fullStr | MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title_full_unstemmed | MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title_short | MR Imaging of Fetuses to Evaluate Placental Insufficiency |
title_sort | mr imaging of fetuses to evaluate placental insufficiency |
topic | Major Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600058/ https://www.ncbi.nlm.nih.gov/pubmed/26607809 http://dx.doi.org/10.2463/mrms.mp.2015-0051 |
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