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Salmon: fast and bias-aware quantification of transcript expression using dual-phase inference
We introduce Salmon, a method for quantifying transcript abundance from RNA-seq reads that is accurate and fast. Salmon is the first transcriptome-wide quantifier to correct for fragment GC content bias, which we demonstrate substantially improves the accuracy of abundance estimates and the reliabil...
Autores principales: | Patro, Rob, Duggal, Geet, Love, Michael I, Irizarry, Rafael A, Kingsford, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600148/ https://www.ncbi.nlm.nih.gov/pubmed/28263959 http://dx.doi.org/10.1038/nmeth.4197 |
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