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Modeling antibiotic treatment in hospitals: A systematic approach shows benefits of combination therapy over cycling, mixing, and mono-drug therapies
Multiple treatment strategies are available for empiric antibiotic therapy in hospitals, but neither clinical studies nor theoretical investigations have yielded a clear picture when which strategy is optimal and why. Extending earlier work of others and us, we present a mathematical model capturing...
Autores principales: | Tepekule, Burcu, Uecker, Hildegard, Derungs, Isabel, Frenoy, Antoine, Bonhoeffer, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600366/ https://www.ncbi.nlm.nih.gov/pubmed/28915236 http://dx.doi.org/10.1371/journal.pcbi.1005745 |
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