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DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
Well-known epigenetic DNA modifications in mammals include the addition of a methyl group and a hydroxyl group to cytosine, resulting in 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) respectively. In contrast, the abundance and the functional implications of these modifications in invert...
Autores principales: | Rasmussen, Erik M.K., Vågbø, Cathrine B., Münch, Daniel, Krokan, Hans E., Klungland, Arne, Amdam, Gro V., Dahl, John Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600429/ https://www.ncbi.nlm.nih.gov/pubmed/28955859 http://dx.doi.org/10.1016/j.bbrep.2016.02.011 |
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