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An HTRF based high-throughput screening for discovering chemical compounds that inhibit the interaction between Trypanosoma brucei Pex5p and Pex14p

The glycosome, a peroxisome-related organelle, is essential for the growth and survival of trypanosomatid protozoa. In glycosome biogenesis, Pex5p recognizes newly synthesized glycosomal matrix proteins via peroxisome-targeting signal type-1 (PTS-1) and transports them into glycosomes through an int...

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Detalles Bibliográficos
Autores principales:	Watanabe, Yuichi, Kawaguchi, Kosuke, Saito, Syuken, Okabe, Takayoshi, Yonesu, Kiyoaki, Egashira, Shinichiro, Kameya, Masafumi, Morita, Masashi, Kashiwayama, Yoshinori, Imanaka, Tsuneo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600434/ https://www.ncbi.nlm.nih.gov/pubmed/28955883 http://dx.doi.org/10.1016/j.bbrep.2016.05.004

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