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AR-13, a Celecoxib Derivative, Directly Kills Francisella In Vitro and Aids Clearance and Mouse Survival In Vivo
Francisella tularensis (F. tularensis) is the causative agent of tularemia and is classified as a Tier 1 select agent. No licensed vaccine is currently available in the United States and treatment of tularemia is confined to few antibiotics. In this study, we demonstrate that AR-13, a derivative of...
Autores principales: | Hoang, Ky V., Adcox, Haley E., Fitch, James R., Gordon, David M., Curry, Heather M., Schlesinger, Larry S., White, Peter, Gunn, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600997/ https://www.ncbi.nlm.nih.gov/pubmed/28955308 http://dx.doi.org/10.3389/fmicb.2017.01695 |
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