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Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells

Using high-throughput small molecule screening targeting furin gene, we identified that phorbol esters dPPA (12-Deoxyphorbol 13-phenylacetate 20-acetate) and dPA (12-Deoxyphorbol 13-acetate) significantly increased furin protein and mRNA expression in SH-SY5Y cells. This effect was prevented by PKC...

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Detalles Bibliográficos
Autores principales:	Zha, Jing-Si, Zhu, Bing-Lin, Liu, Lu, Lai, Yu-Jie, Long, Yan, Hu, Xiao-Tong, Deng, Xiao-Juan, Wang, Xue-Feng, Yan, Zhen, Chen, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601129/ https://www.ncbi.nlm.nih.gov/pubmed/28947961 http://dx.doi.org/10.18632/oncotarget.18569

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