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Chinese medicine Ginseng and Astragalus granules ameliorate autoimmune diabetes by upregulating both CD4+FoxP3+ and CD8+CD122+PD1+ regulatory T cells
Type 1 diabetes mellitus (T1DM) is an autoimmune disease mainly mediated by effector T cells that are activated by autoantigen, thereby resulting in the destruction of pancreatic islets and deficiency of insulin. Cyclosporine is widely used as an immunosuppressant that suppresses autoimmunity in cli...
Autores principales: | Wang, Yeshu, Xie, Qingfeng, Liang, Chun-Ling, Zeng, Qiaohuang, Dai, Zhenhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601132/ https://www.ncbi.nlm.nih.gov/pubmed/28947964 http://dx.doi.org/10.18632/oncotarget.18732 |
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