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NOTCH1 activates the Wnt/β-catenin signaling pathway in colon cancer
PURPOSE AND METHODS: The translocation of β-catenin/CTNNB1 to the nucleus activates Wnt signaling and cell proliferation; however, the precise mechanism underlying this phenomenon remains unknown. Previous reports have provided evidence that NOTCH1 is involved in the Wnt signaling pathway. Therefore...
Autores principales: | Ishiguro, Hideyuki, Okubo, Tomotaka, Kuwabara, Yoshiyuki, Kimura, Masahiro, Mitsui, Akira, Sugito, Nobuyoshi, Ogawa, Ryo, Katada, Takeyasu, Tanaka, Tatsuya, Shiozaki, Midori, Mizoguchi, Koji, Samoto, Yosuke, Matsuo, Yoichi, Takahashi, Hiroki, Takiguchi, Shuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601146/ https://www.ncbi.nlm.nih.gov/pubmed/28947978 http://dx.doi.org/10.18632/oncotarget.19534 |
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