Cargando…
Genetic progression in gastrointestinal stromal tumors: mechanisms and molecular interventions
Gastrointestinal stromal tumors (GISTs) are the most common sarcomas in humans. Constitutively activating mutations in the KIT or PDGFRA receptor tyrosine kinases are the initiating oncogenic events. Most metastatic GISTs respond dramatically to therapies with KIT/PDGFRA inhibitors. Asymptomatic and...
Autores principales: | Li, Ke, Cheng, Haibo, Li, Zhang, Pang, Yuzhi, Jia, Xiaona, Xie, Feifei, Hu, Guohong, Cai, Qingping, Wang, Yuexiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601165/ https://www.ncbi.nlm.nih.gov/pubmed/28947997 http://dx.doi.org/10.18632/oncotarget.16014 |
Ejemplares similares
-
Update on Molecular Genetics of Gastrointestinal Stromal Tumors
por: Brčić, Iva, et al.
Publicado: (2021) -
Oncogenic and drug-sensitive RET mutations in human epithelial ovarian cancer
por: Guan, Luyao, et al.
Publicado: (2020) -
Genetic Characterization of Molecular Targets in Korean Patients with Gastrointestinal Stromal Tumors
por: Park, Joonhong, et al.
Publicado: (2020) -
Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs)
por: Heinrich, Michael C., et al.
Publicado: (2019) -
Clinical Diagnosis of Gastrointestinal Stromal Tumor (GIST): From the Molecular Genetic Point of View
por: Wu, Chiao-En, et al.
Publicado: (2019)