Cargando…
Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading
OBJECTIVE: Short-term neurectomy-induced disuse (SN) has been shown to restore load responses in aged mice. We examined whether this restoration was further enhanced in both cortical and trabecular bone by simply extending the SN. METHODS: Following load: strain calibration, tibiae in female C57BL/J...
Autores principales: | Souza, R. De, Javaheri, B., Collinson, R.S., Chenu, C., Shefelbine, S.J., Lee, P.D., Pitsillides, A.A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Society of Musculoskeletal and Neuronal Interactions
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601267/ https://www.ncbi.nlm.nih.gov/pubmed/28860424 |
Ejemplares similares
-
Predicting cortical bone adaptation to axial loading in the mouse tibia
por: Pereira, A. F., et al.
Publicado: (2015) -
Age and Sex Differences in Load‐Induced Tibial Cortical Bone Surface Strain Maps
por: Carriero, Alessandra, et al.
Publicado: (2021) -
Spatial relationship between bone formation and mechanical stimulus within cortical bone: Combining 3D fluorochrome mapping and poroelastic finite element modelling
por: Carriero, A., et al.
Publicado: (2018) -
Sciatic neurectomy-related cortical bone loss exhibits delayed onset yet stabilises more rapidly than trabecular bone
por: Monzem, Samuel, et al.
Publicado: (2021) -
Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response
por: Javaheri, Behzad, et al.
Publicado: (2018)