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BMPR2 promotes invasion and metastasis via the RhoA-ROCK-LIMK2 pathway in human osteosarcoma cells

Bone morphogenetic protein receptor 2 (BMPR2) has been identified in several types of cancer. However, its role in osteosarcoma is largely unknown. We systematically investigated the role of BMPR2 in osteosarcoma cell lines, human tissue samples and xenograft models. The relationship between BMPR2 e...

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Detalles Bibliográficos
Autores principales: Wang, Shidong, Ren, Tingting, Jiao, Guangjun, Huang, Yi, Bao, Xing, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Sun, Kunkun, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601680/
https://www.ncbi.nlm.nih.gov/pubmed/28938584
http://dx.doi.org/10.18632/oncotarget.17382