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Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis

The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications...

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Detalles Bibliográficos
Autores principales: Surov, Alexey, Meyer, Hans Jonas, Wienke, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601748/
https://www.ncbi.nlm.nih.gov/pubmed/28938652
http://dx.doi.org/10.18632/oncotarget.17752
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author Surov, Alexey
Meyer, Hans Jonas
Wienke, Andreas
author_facet Surov, Alexey
Meyer, Hans Jonas
Wienke, Andreas
author_sort Surov, Alexey
collection PubMed
description The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications in English were extracted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) was used for the research. Overall, 39 publications with 1530 patients were included into the analysis. The following data were extracted from the literature: authors, year of publication, number of patients, tumor type, and correlation coefficients. The pooled correlation coefficient for all studies was ρ = -0.56 (95 % CI = [−0.62; −0.50]),. Correlation coefficients ranged from ρ =−0.25 (95 % CI = [−0.63; 0.12]) in lymphoma to ρ=−0.66 (95 % CI = [−0.85; −0.47]) in glioma. Other coefficients were as follows: ovarian cancer, ρ = −0.64 (95% CI = [−0.76; −0.52]); lung cancer, ρ = −0.63 (95 % CI = [−0.78; −0.48]); uterine cervical cancer, ρ = −0.57 (95 % CI = [−0.80; −0.34]); prostatic cancer, ρ = −0.56 (95 % CI = [−0.69; −0.42]); renal cell carcinoma, ρ = −0.53 (95 % CI = [−0.93; −0.13]); head and neck squamous cell carcinoma, ρ = −0.53 (95 % CI = [-0.74; −0.32]); breast cancer, ρ = −0.48 (95 % CI = [−0.74; −0.23]); and meningioma, ρ = -0.45 (95 % CI = [−0.73; −0.17]).
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spelling pubmed-56017482017-09-21 Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis Surov, Alexey Meyer, Hans Jonas Wienke, Andreas Oncotarget Meta-Analysis The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications in English were extracted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) was used for the research. Overall, 39 publications with 1530 patients were included into the analysis. The following data were extracted from the literature: authors, year of publication, number of patients, tumor type, and correlation coefficients. The pooled correlation coefficient for all studies was ρ = -0.56 (95 % CI = [−0.62; −0.50]),. Correlation coefficients ranged from ρ =−0.25 (95 % CI = [−0.63; 0.12]) in lymphoma to ρ=−0.66 (95 % CI = [−0.85; −0.47]) in glioma. Other coefficients were as follows: ovarian cancer, ρ = −0.64 (95% CI = [−0.76; −0.52]); lung cancer, ρ = −0.63 (95 % CI = [−0.78; −0.48]); uterine cervical cancer, ρ = −0.57 (95 % CI = [−0.80; −0.34]); prostatic cancer, ρ = −0.56 (95 % CI = [−0.69; −0.42]); renal cell carcinoma, ρ = −0.53 (95 % CI = [−0.93; −0.13]); head and neck squamous cell carcinoma, ρ = −0.53 (95 % CI = [-0.74; −0.32]); breast cancer, ρ = −0.48 (95 % CI = [−0.74; −0.23]); and meningioma, ρ = -0.45 (95 % CI = [−0.73; −0.17]). Impact Journals LLC 2017-05-10 /pmc/articles/PMC5601748/ /pubmed/28938652 http://dx.doi.org/10.18632/oncotarget.17752 Text en Copyright: © 2017 Surov et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (http://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Meta-Analysis
Surov, Alexey
Meyer, Hans Jonas
Wienke, Andreas
Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title_full Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title_fullStr Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title_full_unstemmed Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title_short Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
title_sort correlation between apparent diffusion coefficient (adc) and cellularity is different in several tumors: a meta-analysis
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601748/
https://www.ncbi.nlm.nih.gov/pubmed/28938652
http://dx.doi.org/10.18632/oncotarget.17752
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