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Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis
The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601748/ https://www.ncbi.nlm.nih.gov/pubmed/28938652 http://dx.doi.org/10.18632/oncotarget.17752 |
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author | Surov, Alexey Meyer, Hans Jonas Wienke, Andreas |
author_facet | Surov, Alexey Meyer, Hans Jonas Wienke, Andreas |
author_sort | Surov, Alexey |
collection | PubMed |
description | The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications in English were extracted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) was used for the research. Overall, 39 publications with 1530 patients were included into the analysis. The following data were extracted from the literature: authors, year of publication, number of patients, tumor type, and correlation coefficients. The pooled correlation coefficient for all studies was ρ = -0.56 (95 % CI = [−0.62; −0.50]),. Correlation coefficients ranged from ρ =−0.25 (95 % CI = [−0.63; 0.12]) in lymphoma to ρ=−0.66 (95 % CI = [−0.85; −0.47]) in glioma. Other coefficients were as follows: ovarian cancer, ρ = −0.64 (95% CI = [−0.76; −0.52]); lung cancer, ρ = −0.63 (95 % CI = [−0.78; −0.48]); uterine cervical cancer, ρ = −0.57 (95 % CI = [−0.80; −0.34]); prostatic cancer, ρ = −0.56 (95 % CI = [−0.69; −0.42]); renal cell carcinoma, ρ = −0.53 (95 % CI = [−0.93; −0.13]); head and neck squamous cell carcinoma, ρ = −0.53 (95 % CI = [-0.74; −0.32]); breast cancer, ρ = −0.48 (95 % CI = [−0.74; −0.23]); and meningioma, ρ = -0.45 (95 % CI = [−0.73; −0.17]). |
format | Online Article Text |
id | pubmed-5601748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-56017482017-09-21 Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis Surov, Alexey Meyer, Hans Jonas Wienke, Andreas Oncotarget Meta-Analysis The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library was screened for associations between ADC and cell count in different tumors up to September 2016. Only publications in English were extracted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) was used for the research. Overall, 39 publications with 1530 patients were included into the analysis. The following data were extracted from the literature: authors, year of publication, number of patients, tumor type, and correlation coefficients. The pooled correlation coefficient for all studies was ρ = -0.56 (95 % CI = [−0.62; −0.50]),. Correlation coefficients ranged from ρ =−0.25 (95 % CI = [−0.63; 0.12]) in lymphoma to ρ=−0.66 (95 % CI = [−0.85; −0.47]) in glioma. Other coefficients were as follows: ovarian cancer, ρ = −0.64 (95% CI = [−0.76; −0.52]); lung cancer, ρ = −0.63 (95 % CI = [−0.78; −0.48]); uterine cervical cancer, ρ = −0.57 (95 % CI = [−0.80; −0.34]); prostatic cancer, ρ = −0.56 (95 % CI = [−0.69; −0.42]); renal cell carcinoma, ρ = −0.53 (95 % CI = [−0.93; −0.13]); head and neck squamous cell carcinoma, ρ = −0.53 (95 % CI = [-0.74; −0.32]); breast cancer, ρ = −0.48 (95 % CI = [−0.74; −0.23]); and meningioma, ρ = -0.45 (95 % CI = [−0.73; −0.17]). Impact Journals LLC 2017-05-10 /pmc/articles/PMC5601748/ /pubmed/28938652 http://dx.doi.org/10.18632/oncotarget.17752 Text en Copyright: © 2017 Surov et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (http://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Meta-Analysis Surov, Alexey Meyer, Hans Jonas Wienke, Andreas Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title | Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title_full | Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title_fullStr | Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title_full_unstemmed | Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title_short | Correlation between apparent diffusion coefficient (ADC) and cellularity is different in several tumors: a meta-analysis |
title_sort | correlation between apparent diffusion coefficient (adc) and cellularity is different in several tumors: a meta-analysis |
topic | Meta-Analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601748/ https://www.ncbi.nlm.nih.gov/pubmed/28938652 http://dx.doi.org/10.18632/oncotarget.17752 |
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