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High-yield production of “difficult-to-express” proteins in a continuous exchange cell-free system based on CHO cell lysates
Cell-free protein synthesis (CFPS) represents a promising technology for efficient protein production targeting especially so called “difficult-to-express” proteins whose synthesis is challenging in conventional in vivo protein production platforms. Chinese hamster ovary (CHO) cells are one of the m...
Autores principales: | Thoring, Lena, Dondapati, Srujan K., Stech, Marlitt, Wüstenhagen, Doreen A., Kubick, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601898/ https://www.ncbi.nlm.nih.gov/pubmed/28916746 http://dx.doi.org/10.1038/s41598-017-12188-8 |
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