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Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression
Although A Disintegrin And Metalloproteinase 8 (ADAM8) is not crucial for tissue development and homeostasis, it has been implicated in various inflammatory diseases by regulating processes like immune cell recruitment and activation. ADAM8 expression has been associated with human atherosclerosis d...
Autores principales: | Theodorou, Kosta, van der Vorst, Emiel P. C., Gijbels, Marion J., Wolfs, Ine M. J., Jeurissen, Mike, Theelen, Thomas L., Sluimer, Judith C., Wijnands, Erwin, Cleutjens, Jack P., Li, Yu, Jansen, Yvonne, Weber, Christian, Ludwig, Andreas, Bentzon, Jacob F., Bartsch, Jörg W., Biessen, Erik A. L., Donners, Marjo M. P. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601942/ https://www.ncbi.nlm.nih.gov/pubmed/28916789 http://dx.doi.org/10.1038/s41598-017-10549-x |
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