Determining Ribavirin’s mechanism of action against Lassa virus infection

Ribavirin is a broad spectrum antiviral which inhibits Lassa virus (LASV) replication in vitro but exhibits a minor effect on viremia in vivo. However, ribavirin significantly improves the disease outcome when administered in combination with sub-optimal doses of favipiravir, a strong antiviral drug...

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Detalles Bibliográficos
Autores principales: Carrillo-Bustamante, Paola, Nguyen, Thi Huyen Tram, Oestereich, Lisa, Günther, Stephan, Guedj, Jeremie, Graw, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601963/
https://www.ncbi.nlm.nih.gov/pubmed/28916737
http://dx.doi.org/10.1038/s41598-017-10198-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601963/
https://www.ncbi.nlm.nih.gov/pubmed/28916737
http://dx.doi.org/10.1038/s41598-017-10198-0

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