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Angiotensin II Type 1 Receptor Blockers Inhibit KAT II Activity in the Brain—Its Possible Clinical Applications

Angiotensin II receptor blockers (ARBs) are one of the most frequently recommended antihypertensive drugs. Apart from their activity towards the circulatory system, ARBs also penetrate the blood-brain barrier and display neuroprotective effects. Kynurenic acid (KYNA) is an endogenous metabolite of t...

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Detalles Bibliográficos
Autores principales: Zakrocka, Izabela, Targowska-Duda, Katarzyna M., Wnorowski, Artur, Kocki, Tomasz, Jóźwiak, Krzysztof, Turski, Waldemar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602025/
https://www.ncbi.nlm.nih.gov/pubmed/28733707
http://dx.doi.org/10.1007/s12640-017-9781-2

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