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Angiotensin II Type 1 Receptor Blockers Inhibit KAT II Activity in the Brain—Its Possible Clinical Applications
Angiotensin II receptor blockers (ARBs) are one of the most frequently recommended antihypertensive drugs. Apart from their activity towards the circulatory system, ARBs also penetrate the blood-brain barrier and display neuroprotective effects. Kynurenic acid (KYNA) is an endogenous metabolite of t...
Autores principales: | Zakrocka, Izabela, Targowska-Duda, Katarzyna M., Wnorowski, Artur, Kocki, Tomasz, Jóźwiak, Krzysztof, Turski, Waldemar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602025/ https://www.ncbi.nlm.nih.gov/pubmed/28733707 http://dx.doi.org/10.1007/s12640-017-9781-2 |
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