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Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.

In age-related macular degeneration (AMD) the retinal pigment epithelium (RPE) deteriorates, leading to photoreceptor decay and severe vision loss. New therapeutic strategies aim at RPE replacement by transplantation of pluripotent stem cell (PSC)-derived RPE. Several protocols to generate RPE have...

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Detalles Bibliográficos
Autores principales: Bennis, A., Jacobs, J. G., Catsburg, L. A. E., ten Brink, J. B., Koster, C., Schlingemann, R. O., van Meurs, J., Gorgels, T. G. M. F., Moerland, P. D., Heine, V. M., Bergen, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602068/
https://www.ncbi.nlm.nih.gov/pubmed/28730556
http://dx.doi.org/10.1007/s12015-017-9754-0