An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington’s Disease

Behavioral testing is a critical step in assessing the validity of rodent models of neurodegenerative disease, as well as evaluating the efficacy of pharmacological interventions. In models of Huntington’s disease (HD), a gradual progression of impairments is observed across ages, increasing the nee...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodard, Cameron L., Bolaños, Federico, Boyd, James D., Silasi, Gergely, Murphy, Timothy H., Raymond, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602104/
https://www.ncbi.nlm.nih.gov/pubmed/28929129
http://dx.doi.org/10.1523/ENEURO.0141-17.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602104/
https://www.ncbi.nlm.nih.gov/pubmed/28929129
http://dx.doi.org/10.1523/ENEURO.0141-17.2017

Ejemplares similares