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An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington’s Disease
Behavioral testing is a critical step in assessing the validity of rodent models of neurodegenerative disease, as well as evaluating the efficacy of pharmacological interventions. In models of Huntington’s disease (HD), a gradual progression of impairments is observed across ages, increasing the nee...
Autores principales: | Woodard, Cameron L., Bolaños, Federico, Boyd, James D., Silasi, Gergely, Murphy, Timothy H., Raymond, Lynn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602104/ https://www.ncbi.nlm.nih.gov/pubmed/28929129 http://dx.doi.org/10.1523/ENEURO.0141-17.2017 |
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