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Food and Sex-Related Impacts on the Pharmacokinetics of a Single-Dose of Ginsenoside Compound K in Healthy Subjects
Background and Objectives: Ginsenoside compound K (CK) is a candidate drug for rheumatoid arthritis therapy. This clinical trial was designed to evaluate the effects of food and sex on the pharmacokinetics of CK and its metabolite 20(S)-protopanaxadiol (PPD). Methods: An open-label, single-center, t...
Autores principales: | Chen, Lulu, Zhou, Luping, Wang, Yaqin, Yang, Guoping, Huang, Jie, Tan, Zhirong, Wang, Yicheng, Zhou, Gan, Liao, Jianwei, Ouyang, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602130/ https://www.ncbi.nlm.nih.gov/pubmed/28955238 http://dx.doi.org/10.3389/fphar.2017.00636 |
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