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Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study

BACKGROUND: This study is to investigate the feasibility of low iodine concentration contrast material (CM) combined with low tube voltage and adaptive statistical iterative reconstruction (ASIR) in renal computed tomography angiography (CTA). MATERIAL/METHODS: A total of 136 patients were enrolled...

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Autores principales: Liu, Sulan, Li, Wei, Shi, Hao, Sheng, Huaqiang, Fan, Jingli, He, Jingzhen, Sun, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602168/
https://www.ncbi.nlm.nih.gov/pubmed/28888094
http://dx.doi.org/10.12659/MSM.902917
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author Liu, Sulan
Li, Wei
Shi, Hao
Sheng, Huaqiang
Fan, Jingli
He, Jingzhen
Sun, Hongjun
author_facet Liu, Sulan
Li, Wei
Shi, Hao
Sheng, Huaqiang
Fan, Jingli
He, Jingzhen
Sun, Hongjun
author_sort Liu, Sulan
collection PubMed
description BACKGROUND: This study is to investigate the feasibility of low iodine concentration contrast material (CM) combined with low tube voltage and adaptive statistical iterative reconstruction (ASIR) in renal computed tomography angiography (CTA). MATERIAL/METHODS: A total of 136 patients were enrolled in this prospective trial, and randomly divided into two groups: group A (n=68) and group B (n=68). Group A received 120-kVp and iopromide (370 mg/mL) with filtered back projection (FBP) reconstruction, and group B received 100-kVp and iodixanol (270 mg/mL) with ASIR 40% (ASIR(40)). An equal iodine dose (300 mg/kg body weight) and the same iodine delivery rate (1,500 mg I/s) were given to all patients. Density, image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were measured, and the image quality and visualization of renal arteries were scored. Dose-length product (DLP) and CT dose index volume (CTDIvol) were recorded, and effective doses (ED) were calculated. RESULTS: There was no significant difference in image noise between groups A and B (p>0.05). The vessel attenuation, SNR, and CNR were significantly higher in group B than group A (all p<0.05). The subjective image quality and visualization of renal artery branches were similar in these two groups (p>0.05). Compared with group A, the CTDIvol, DLP, and ED in group B were decreased by 38.58%, 37.24%, and 37.24%, respectively (p=0.000). CONCLUSIONS: Compared with 120-kVp with FBP reconstruction, the protocol of 100-kVp with ASIRP(40) reconstruction provided high-quality renal CTA results, which allowed for reduced iodine concentration and decreased radiation dose.
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spelling pubmed-56021682017-09-22 Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study Liu, Sulan Li, Wei Shi, Hao Sheng, Huaqiang Fan, Jingli He, Jingzhen Sun, Hongjun Med Sci Monit Clinical Research BACKGROUND: This study is to investigate the feasibility of low iodine concentration contrast material (CM) combined with low tube voltage and adaptive statistical iterative reconstruction (ASIR) in renal computed tomography angiography (CTA). MATERIAL/METHODS: A total of 136 patients were enrolled in this prospective trial, and randomly divided into two groups: group A (n=68) and group B (n=68). Group A received 120-kVp and iopromide (370 mg/mL) with filtered back projection (FBP) reconstruction, and group B received 100-kVp and iodixanol (270 mg/mL) with ASIR 40% (ASIR(40)). An equal iodine dose (300 mg/kg body weight) and the same iodine delivery rate (1,500 mg I/s) were given to all patients. Density, image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were measured, and the image quality and visualization of renal arteries were scored. Dose-length product (DLP) and CT dose index volume (CTDIvol) were recorded, and effective doses (ED) were calculated. RESULTS: There was no significant difference in image noise between groups A and B (p>0.05). The vessel attenuation, SNR, and CNR were significantly higher in group B than group A (all p<0.05). The subjective image quality and visualization of renal artery branches were similar in these two groups (p>0.05). Compared with group A, the CTDIvol, DLP, and ED in group B were decreased by 38.58%, 37.24%, and 37.24%, respectively (p=0.000). CONCLUSIONS: Compared with 120-kVp with FBP reconstruction, the protocol of 100-kVp with ASIRP(40) reconstruction provided high-quality renal CTA results, which allowed for reduced iodine concentration and decreased radiation dose. International Scientific Literature, Inc. 2017-09-09 /pmc/articles/PMC5602168/ /pubmed/28888094 http://dx.doi.org/10.12659/MSM.902917 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Liu, Sulan
Li, Wei
Shi, Hao
Sheng, Huaqiang
Fan, Jingli
He, Jingzhen
Sun, Hongjun
Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title_full Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title_fullStr Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title_full_unstemmed Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title_short Low-Dose Scanning Technology Combined with Low-Concentration Contrast Material in Renal Computed Tomography Angiography (CTA): A Preliminary Study
title_sort low-dose scanning technology combined with low-concentration contrast material in renal computed tomography angiography (cta): a preliminary study
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602168/
https://www.ncbi.nlm.nih.gov/pubmed/28888094
http://dx.doi.org/10.12659/MSM.902917
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