Cargando…

Histone deacetylase inhibition induces odor preference memory extension and maintains enhanced AMPA receptor expression in the rat pup model

Histone deacetylase (HDAC) plays a role in synaptic plasticity and long-term memory formation. We hypothesized that trichostatin-A (TSA), an HDAC inhibitor, would promote long-term odor preference memory and maintain enhanced GluA1 receptor levels that have been hypothesized to support memory. We us...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattacharya, Sriya, Mukherjee, Bandhan, Doré, Jules J.E., Yuan, Qi, Harley, Carolyn W., McLean, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602343/
https://www.ncbi.nlm.nih.gov/pubmed/28916629
http://dx.doi.org/10.1101/lm.045799.117