CASTLE Thyroid Tumor: A Case Report and Literature Review

Carcinoma showing thymus-like differentiation is a rare tumor of the thyroid gland, which is structurally similar to thymic tissue. Overall, it has a favorable prognosis. Radiotherapy has been shown to be an effective local treatment, but there have been reports of distant recurrence. It has been su...

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Autores principales: Lominska, Chris, Estes, Christopher Fleighton, Neupane, Prakash C., Shnayder, Y., TenNapel, Mindi J., O’Neil, Maura F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602351/
https://www.ncbi.nlm.nih.gov/pubmed/28955658
http://dx.doi.org/10.3389/fonc.2017.00207
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author Lominska, Chris
Estes, Christopher Fleighton
Neupane, Prakash C.
Shnayder, Y.
TenNapel, Mindi J.
O’Neil, Maura F.
author_facet Lominska, Chris
Estes, Christopher Fleighton
Neupane, Prakash C.
Shnayder, Y.
TenNapel, Mindi J.
O’Neil, Maura F.
author_sort Lominska, Chris
collection PubMed
description Carcinoma showing thymus-like differentiation is a rare tumor of the thyroid gland, which is structurally similar to thymic tissue. Overall, it has a favorable prognosis. Radiotherapy has been shown to be an effective local treatment, but there have been reports of distant recurrence. It has been suggested that adding chemotherapy may decrease the risk of recurrence. Here, we present a case report of a patient with a large tumor and extrathyroidal extension. The patient was treated with surgery, radiotherapy, and cisplatin with acceptable toxicity. The patient is free of locally recurrent or distant disease at 3 years.
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spelling pubmed-56023512017-09-27 CASTLE Thyroid Tumor: A Case Report and Literature Review Lominska, Chris Estes, Christopher Fleighton Neupane, Prakash C. Shnayder, Y. TenNapel, Mindi J. O’Neil, Maura F. Front Oncol Oncology Carcinoma showing thymus-like differentiation is a rare tumor of the thyroid gland, which is structurally similar to thymic tissue. Overall, it has a favorable prognosis. Radiotherapy has been shown to be an effective local treatment, but there have been reports of distant recurrence. It has been suggested that adding chemotherapy may decrease the risk of recurrence. Here, we present a case report of a patient with a large tumor and extrathyroidal extension. The patient was treated with surgery, radiotherapy, and cisplatin with acceptable toxicity. The patient is free of locally recurrent or distant disease at 3 years. Frontiers Media S.A. 2017-09-13 /pmc/articles/PMC5602351/ /pubmed/28955658 http://dx.doi.org/10.3389/fonc.2017.00207 Text en Copyright © 2017 Lominska, Estes, Neupane, Shnayder, TenNapel and O’Neil. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Lominska, Chris
Estes, Christopher Fleighton
Neupane, Prakash C.
Shnayder, Y.
TenNapel, Mindi J.
O’Neil, Maura F.
CASTLE Thyroid Tumor: A Case Report and Literature Review
title CASTLE Thyroid Tumor: A Case Report and Literature Review
title_full CASTLE Thyroid Tumor: A Case Report and Literature Review
title_fullStr CASTLE Thyroid Tumor: A Case Report and Literature Review
title_full_unstemmed CASTLE Thyroid Tumor: A Case Report and Literature Review
title_short CASTLE Thyroid Tumor: A Case Report and Literature Review
title_sort castle thyroid tumor: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602351/
https://www.ncbi.nlm.nih.gov/pubmed/28955658
http://dx.doi.org/10.3389/fonc.2017.00207
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