Ypt4 and lvs1 regulate vacuolar size and function in Schizosaccharomyces pombe

The yeast vacuole plays key roles in cellular stress responses. Here, we show that deletion of lvs1, the fission yeast homolog of the Chediak-Higashi Syndrome CHS1/LYST gene, increases vacuolar size, similar to deletion of the Rab4 homolog ypt4. Overexpression of lvs1-YFP rescued vacuolar size in yp...

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Detalles Bibliográficos
Autores principales: Rains, Addison, Bryant, Yorisha, Dorsett, Kaitlyn A., Culver, Austin, Egbaria, Jamal, Williams, Austin, Barnes, Matt, Lamere, Raeann, Rossi, Austin R., Waldrep, Stephanie C., Wilder, Caroline, Kliossis, Elliot, Styers, Melanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Letter to the Editor: Cellular Logistics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602425/
https://www.ncbi.nlm.nih.gov/pubmed/28944093
http://dx.doi.org/10.1080/21592799.2017.1335270

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