A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia

Gene signatures have been associated with outcome in pediatric acute lymphoblastic leukemia (ALL) and other malignancies. However, determining the molecular drivers of these expression changes remains challenging. In ALL blasts, the p53 tumor suppressor is the primary regulator of the apoptotic resp...

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Detalles Bibliográficos
Autores principales: Bainer, Russell O, Trendowski, Matthew R, Cheng, Cheng, Pei, Deqing, Yang, Wenjian, Paugh, Steven W, Goss, Kathleen H, Skol, Andrew D, Pavlidis, Paul, Pui, Ching-Hon, Gilliam, T Conrad, Evans, William E, Onel, Kenan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602435/
https://www.ncbi.nlm.nih.gov/pubmed/28979163
http://dx.doi.org/10.2147/CMAR.S139864

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