Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway

Fibrosis is the major pathological feature of diabetic kidney disease (DKD). Autophagy, a process to maintain metabolic homeostasis, is obviously inhibited in DKD. Triptolide (TP) is a traditional Chinese medicine extract known for immune suppression and anti-inflammatory and anti-cancer activities....

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Detalles Bibliográficos
Autores principales: Li, Xiao-yu, Wang, Shan-shan, Han, Zhe, Han, Fei, Chang, Yun-peng, Yang, Yang, Xue, Mei, Sun, Bei, Chen, Li-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602517/
https://www.ncbi.nlm.nih.gov/pubmed/29246323
http://dx.doi.org/10.1016/j.omtn.2017.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602517/
https://www.ncbi.nlm.nih.gov/pubmed/29246323
http://dx.doi.org/10.1016/j.omtn.2017.08.011

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