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A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identificati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602620/ https://www.ncbi.nlm.nih.gov/pubmed/28948050 http://dx.doi.org/10.1155/2017/1370751 |
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author | Vezzoli, Marika Bonardelli, Stefano Peroni, Michele Ravanelli, Marco Garrafa, Emirena |
author_facet | Vezzoli, Marika Bonardelli, Stefano Peroni, Michele Ravanelli, Marco Garrafa, Emirena |
author_sort | Vezzoli, Marika |
collection | PubMed |
description | OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identification of calcification progression of the aneurysm. DESIGN: Risk factors were collected and cell blood count was performed in patients with AAA and patients were analyzed for the presence of aorta calcification using CT angiography. RESULTS: We found no association of calcification grade with risk factors for AAA but we found a strong association between MCV, MCH, and calcification grade. Instead, no association was found with the other parameter that we analyzed. CONCLUSIONS: In this study, we demonstrate that biomarkers such as MCV and MCH could have potential important information about AAA calcification progression and could be useful to discriminate between those patients that should undergo a rapid imaging, thus allowing prompt initiation of treatment of suspicious patients that do not need imaging repetition. |
format | Online Article Text |
id | pubmed-5602620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-56026202017-09-25 A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm Vezzoli, Marika Bonardelli, Stefano Peroni, Michele Ravanelli, Marco Garrafa, Emirena Int J Vasc Med Research Article OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identification of calcification progression of the aneurysm. DESIGN: Risk factors were collected and cell blood count was performed in patients with AAA and patients were analyzed for the presence of aorta calcification using CT angiography. RESULTS: We found no association of calcification grade with risk factors for AAA but we found a strong association between MCV, MCH, and calcification grade. Instead, no association was found with the other parameter that we analyzed. CONCLUSIONS: In this study, we demonstrate that biomarkers such as MCV and MCH could have potential important information about AAA calcification progression and could be useful to discriminate between those patients that should undergo a rapid imaging, thus allowing prompt initiation of treatment of suspicious patients that do not need imaging repetition. Hindawi 2017 2017-08-30 /pmc/articles/PMC5602620/ /pubmed/28948050 http://dx.doi.org/10.1155/2017/1370751 Text en Copyright © 2017 Marika Vezzoli et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Vezzoli, Marika Bonardelli, Stefano Peroni, Michele Ravanelli, Marco Garrafa, Emirena A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title | A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title_full | A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title_fullStr | A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title_full_unstemmed | A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title_short | A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm |
title_sort | simple blood test, such as complete blood count, can predict calcification grade of abdominal aortic aneurysm |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602620/ https://www.ncbi.nlm.nih.gov/pubmed/28948050 http://dx.doi.org/10.1155/2017/1370751 |
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