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A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm

OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identificati...

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Autores principales: Vezzoli, Marika, Bonardelli, Stefano, Peroni, Michele, Ravanelli, Marco, Garrafa, Emirena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602620/
https://www.ncbi.nlm.nih.gov/pubmed/28948050
http://dx.doi.org/10.1155/2017/1370751
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author Vezzoli, Marika
Bonardelli, Stefano
Peroni, Michele
Ravanelli, Marco
Garrafa, Emirena
author_facet Vezzoli, Marika
Bonardelli, Stefano
Peroni, Michele
Ravanelli, Marco
Garrafa, Emirena
author_sort Vezzoli, Marika
collection PubMed
description OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identification of calcification progression of the aneurysm. DESIGN: Risk factors were collected and cell blood count was performed in patients with AAA and patients were analyzed for the presence of aorta calcification using CT angiography. RESULTS: We found no association of calcification grade with risk factors for AAA but we found a strong association between MCV, MCH, and calcification grade. Instead, no association was found with the other parameter that we analyzed. CONCLUSIONS: In this study, we demonstrate that biomarkers such as MCV and MCH could have potential important information about AAA calcification progression and could be useful to discriminate between those patients that should undergo a rapid imaging, thus allowing prompt initiation of treatment of suspicious patients that do not need imaging repetition.
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spelling pubmed-56026202017-09-25 A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm Vezzoli, Marika Bonardelli, Stefano Peroni, Michele Ravanelli, Marco Garrafa, Emirena Int J Vasc Med Research Article OBJECTIVE: The pathogenesis of abdominal aortic aneurysm (AAA) is complex and different factors, including calcification, are linked to increased complications. This study was conducted in order to verify if classical risk factors for AAA and cell blood count parameter could help in the identification of calcification progression of the aneurysm. DESIGN: Risk factors were collected and cell blood count was performed in patients with AAA and patients were analyzed for the presence of aorta calcification using CT angiography. RESULTS: We found no association of calcification grade with risk factors for AAA but we found a strong association between MCV, MCH, and calcification grade. Instead, no association was found with the other parameter that we analyzed. CONCLUSIONS: In this study, we demonstrate that biomarkers such as MCV and MCH could have potential important information about AAA calcification progression and could be useful to discriminate between those patients that should undergo a rapid imaging, thus allowing prompt initiation of treatment of suspicious patients that do not need imaging repetition. Hindawi 2017 2017-08-30 /pmc/articles/PMC5602620/ /pubmed/28948050 http://dx.doi.org/10.1155/2017/1370751 Text en Copyright © 2017 Marika Vezzoli et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Vezzoli, Marika
Bonardelli, Stefano
Peroni, Michele
Ravanelli, Marco
Garrafa, Emirena
A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title_full A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title_fullStr A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title_full_unstemmed A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title_short A Simple Blood Test, Such as Complete Blood Count, Can Predict Calcification Grade of Abdominal Aortic Aneurysm
title_sort simple blood test, such as complete blood count, can predict calcification grade of abdominal aortic aneurysm
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602620/
https://www.ncbi.nlm.nih.gov/pubmed/28948050
http://dx.doi.org/10.1155/2017/1370751
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