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Rod metabolic demand drives progression in retinopathies
Various factors are thought to cause the development and progression of disease in macular degeneration, diabetic retinopathy, and retinitis pigmentosa. Some of the deleterious processes include oxidative stress, hypoxia, metabolic derangement, genetics, and vasculopathy. In this review, we present...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602704/ https://www.ncbi.nlm.nih.gov/pubmed/29018679 http://dx.doi.org/10.1016/j.tjo.2015.06.002 |
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author | Lin, Michael K. Kim, Soo Hyun Zhang, Lijuan Tsai, Yi-Ting Tsang, Stephen H. |
author_facet | Lin, Michael K. Kim, Soo Hyun Zhang, Lijuan Tsai, Yi-Ting Tsang, Stephen H. |
author_sort | Lin, Michael K. |
collection | PubMed |
description | Various factors are thought to cause the development and progression of disease in macular degeneration, diabetic retinopathy, and retinitis pigmentosa. Some of the deleterious processes include oxidative stress, hypoxia, metabolic derangement, genetics, and vasculopathy. In this review, we present a unified theory for the pathophysiology of several retinopathies based on the unique and intense metabolism of rod photoreceptors. |
format | Online Article Text |
id | pubmed-5602704 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56027042017-10-10 Rod metabolic demand drives progression in retinopathies Lin, Michael K. Kim, Soo Hyun Zhang, Lijuan Tsai, Yi-Ting Tsang, Stephen H. Taiwan J Ophthalmol Review Article Various factors are thought to cause the development and progression of disease in macular degeneration, diabetic retinopathy, and retinitis pigmentosa. Some of the deleterious processes include oxidative stress, hypoxia, metabolic derangement, genetics, and vasculopathy. In this review, we present a unified theory for the pathophysiology of several retinopathies based on the unique and intense metabolism of rod photoreceptors. Medknow Publications & Media Pvt Ltd 2015 2015-08-25 /pmc/articles/PMC5602704/ /pubmed/29018679 http://dx.doi.org/10.1016/j.tjo.2015.06.002 Text en Copyright: © 2015, The Ophthalmologic Society of Taiwan http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Lin, Michael K. Kim, Soo Hyun Zhang, Lijuan Tsai, Yi-Ting Tsang, Stephen H. Rod metabolic demand drives progression in retinopathies |
title | Rod metabolic demand drives progression in retinopathies |
title_full | Rod metabolic demand drives progression in retinopathies |
title_fullStr | Rod metabolic demand drives progression in retinopathies |
title_full_unstemmed | Rod metabolic demand drives progression in retinopathies |
title_short | Rod metabolic demand drives progression in retinopathies |
title_sort | rod metabolic demand drives progression in retinopathies |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602704/ https://www.ncbi.nlm.nih.gov/pubmed/29018679 http://dx.doi.org/10.1016/j.tjo.2015.06.002 |
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