Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites

Proteases have been implicated in a variety of developmental processes during the malaria parasite lifecycle. In particular, invasion and egress of the parasite from the infected hepatocyte and erythrocyte, critically depend on protease activity. Although falcipain-1 was the first cysteine protease...

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Detalles Bibliográficos
Autores principales: Hopp, Christine S., Bennett, Brandy L., Mishra, Satish, Lehmann, Christine, Hanson, Kirsten K., Lin, Jing-wen, Rousseau, Kimberly, Carvalho, Filomena A., van der Linden, Wouter A., Santos, Nuno C., Bogyo, Matthew, Khan, Shahid M., Heussler, Volker, Sinnis, Photini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602738/
https://www.ncbi.nlm.nih.gov/pubmed/28922424
http://dx.doi.org/10.1371/journal.ppat.1006586

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