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Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy

BACKGROUND: Patients with esophageal cancer and a history of gastrectomy or concurrent gastric cancer undergo not only esophagectomy but also total gastrectomy. The goal of this study is to evaluate the postoperative quality of life (QOL) and dysfunction of these patients using two postoperative que...

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Autores principales: Saito, Shin, Nakamura, Misuzu, Hosoya, Yoshinori, Kitayama, Joji, Lefor, Alan Kawarai, Sata, Naohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602742/
https://www.ncbi.nlm.nih.gov/pubmed/28948022
http://dx.doi.org/10.1016/j.amsu.2017.08.016
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author Saito, Shin
Nakamura, Misuzu
Hosoya, Yoshinori
Kitayama, Joji
Lefor, Alan Kawarai
Sata, Naohiro
author_facet Saito, Shin
Nakamura, Misuzu
Hosoya, Yoshinori
Kitayama, Joji
Lefor, Alan Kawarai
Sata, Naohiro
author_sort Saito, Shin
collection PubMed
description BACKGROUND: Patients with esophageal cancer and a history of gastrectomy or concurrent gastric cancer undergo not only esophagectomy but also total gastrectomy. The goal of this study is to evaluate the postoperative quality of life (QOL) and dysfunction of these patients using two postoperative questionnaires. MATERIALS AND METHODS: From 1999 to 2015, 41 patients underwent concurrent esophagectomy and total gastrectomy. A jejunal pedicle with the subcutaneous supercharge technique was used for reconstruction. Patients were divided into two groups, including those undergoing concurrent esophagostomy and gastrectomy (Group 1), and those undergoing esophagectomy alone (Group 2, history of previous gastrectomy). Patients were analyzed by time interval, including patients within three years of surgery (Group A) and those more than three years after surgery (Group B). RESULTS: Eighteen patients completed the questionnaires. The mean DAUGS20 score was 26.4 ± 13.2. The DAUGS20 scores of groups 1 (N = 7) and 2 (N = 11) were 25.4 ± 12.5 and 27 ± 15.4 (p = 0.58), respectively. Global health status scored by the EORTC QLQC-30 were 71.4 ± 18.5 in group 1 and 67.4 ± 22.8 in group 2 (p = 0.85). DAUGS20 scores of group A (N = 10) and B (N = 8) were 28.1 ± 12.4 and 23.3 ± 14.4 (p = 0.35). No significant differences were found between groups A and B regarding the QLQ-C30 scores. CONCLUSION: DAUGS20 and QLQ-C30 scores showed no significant differences between groups 1 and 2 or groups A and B. These results suggest that postoperative QOL and dysfunction may be influenced more by current status than by surgical history and postoperative interval. Previous reports describe a DAUGS 20 score after gastrectomy of 27.8 and after esophagectomy of 36.1. The DAUGS20 score of these 18 patients is lower than DAUGS20 scores for patients undergoing either operation alone. Reconstruction using a subcutaneously placed jejunal segment seems to be reasonable.
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spelling pubmed-56027422017-09-25 Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy Saito, Shin Nakamura, Misuzu Hosoya, Yoshinori Kitayama, Joji Lefor, Alan Kawarai Sata, Naohiro Ann Med Surg (Lond) Original Research BACKGROUND: Patients with esophageal cancer and a history of gastrectomy or concurrent gastric cancer undergo not only esophagectomy but also total gastrectomy. The goal of this study is to evaluate the postoperative quality of life (QOL) and dysfunction of these patients using two postoperative questionnaires. MATERIALS AND METHODS: From 1999 to 2015, 41 patients underwent concurrent esophagectomy and total gastrectomy. A jejunal pedicle with the subcutaneous supercharge technique was used for reconstruction. Patients were divided into two groups, including those undergoing concurrent esophagostomy and gastrectomy (Group 1), and those undergoing esophagectomy alone (Group 2, history of previous gastrectomy). Patients were analyzed by time interval, including patients within three years of surgery (Group A) and those more than three years after surgery (Group B). RESULTS: Eighteen patients completed the questionnaires. The mean DAUGS20 score was 26.4 ± 13.2. The DAUGS20 scores of groups 1 (N = 7) and 2 (N = 11) were 25.4 ± 12.5 and 27 ± 15.4 (p = 0.58), respectively. Global health status scored by the EORTC QLQC-30 were 71.4 ± 18.5 in group 1 and 67.4 ± 22.8 in group 2 (p = 0.85). DAUGS20 scores of group A (N = 10) and B (N = 8) were 28.1 ± 12.4 and 23.3 ± 14.4 (p = 0.35). No significant differences were found between groups A and B regarding the QLQ-C30 scores. CONCLUSION: DAUGS20 and QLQ-C30 scores showed no significant differences between groups 1 and 2 or groups A and B. These results suggest that postoperative QOL and dysfunction may be influenced more by current status than by surgical history and postoperative interval. Previous reports describe a DAUGS 20 score after gastrectomy of 27.8 and after esophagectomy of 36.1. The DAUGS20 score of these 18 patients is lower than DAUGS20 scores for patients undergoing either operation alone. Reconstruction using a subcutaneously placed jejunal segment seems to be reasonable. Elsevier 2017-08-24 /pmc/articles/PMC5602742/ /pubmed/28948022 http://dx.doi.org/10.1016/j.amsu.2017.08.016 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Saito, Shin
Nakamura, Misuzu
Hosoya, Yoshinori
Kitayama, Joji
Lefor, Alan Kawarai
Sata, Naohiro
Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title_full Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title_fullStr Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title_full_unstemmed Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title_short Postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
title_sort postoperative quality of life and dysfunction in patients after combined total gastrectomy and esophagectomy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602742/
https://www.ncbi.nlm.nih.gov/pubmed/28948022
http://dx.doi.org/10.1016/j.amsu.2017.08.016
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