Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study

• 7 of 9 patients with GGE reduced ≥ 50% their tonic–clonic seizure frequency on LCM. • All 7 patients remained seizure free for > 1 year, and 2 of them for > 5 years. • In 2 of the 9 patients, both with Juvenile Absence Epilepsy, absences aggravated. • One aggravation consisted on a myoclonia...

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Autores principales: Abarrategui, Belén, García-García, María Eugenia, Toledano, Rafael, Parejo-Carbonell, Beatriz, Gil-Nagel, Antonio, García-Morales, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602820/
https://www.ncbi.nlm.nih.gov/pubmed/28948142
http://dx.doi.org/10.1016/j.ebcr.2017.08.001
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author Abarrategui, Belén
García-García, María Eugenia
Toledano, Rafael
Parejo-Carbonell, Beatriz
Gil-Nagel, Antonio
García-Morales, Irene
author_facet Abarrategui, Belén
García-García, María Eugenia
Toledano, Rafael
Parejo-Carbonell, Beatriz
Gil-Nagel, Antonio
García-Morales, Irene
author_sort Abarrategui, Belén
collection PubMed
description • 7 of 9 patients with GGE reduced ≥ 50% their tonic–clonic seizure frequency on LCM. • All 7 patients remained seizure free for > 1 year, and 2 of them for > 5 years. • In 2 of the 9 patients, both with Juvenile Absence Epilepsy, absences aggravated. • One aggravation consisted on a myoclonia and absence status, in a patient with no history of myoclonia. • VEEG paralleled clinical improvement but didn't change in a case of absence worsening.
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spelling pubmed-56028202017-09-25 Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study Abarrategui, Belén García-García, María Eugenia Toledano, Rafael Parejo-Carbonell, Beatriz Gil-Nagel, Antonio García-Morales, Irene Epilepsy Behav Case Rep Case Report • 7 of 9 patients with GGE reduced ≥ 50% their tonic–clonic seizure frequency on LCM. • All 7 patients remained seizure free for > 1 year, and 2 of them for > 5 years. • In 2 of the 9 patients, both with Juvenile Absence Epilepsy, absences aggravated. • One aggravation consisted on a myoclonia and absence status, in a patient with no history of myoclonia. • VEEG paralleled clinical improvement but didn't change in a case of absence worsening. Elsevier 2017-08-24 /pmc/articles/PMC5602820/ /pubmed/28948142 http://dx.doi.org/10.1016/j.ebcr.2017.08.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Abarrategui, Belén
García-García, María Eugenia
Toledano, Rafael
Parejo-Carbonell, Beatriz
Gil-Nagel, Antonio
García-Morales, Irene
Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title_full Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title_fullStr Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title_full_unstemmed Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title_short Lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: A clinical and VEEG study
title_sort lacosamide for refractory generalized tonic–clonic seizures of non-focal origin in clinical practice: a clinical and veeg study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602820/
https://www.ncbi.nlm.nih.gov/pubmed/28948142
http://dx.doi.org/10.1016/j.ebcr.2017.08.001
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