Cathepsin B as a potential cystatin M/E target in the mouse hair follicle

Deficiency of the cysteine protease inhibitor cystatin M/E (Cst6) in mice leads to disturbed epidermal cornification, impaired barrier function, and neonatal lethality. We report the rescue of the lethal skin phenotype of ichq (Cst6-deficient; Cst6(−/−)) mice by transgenic, epidermis-specific, reexp...

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Detalles Bibliográficos
Autores principales: Oortveld, Merel A. W., van Vlijmen-Willems, Ivonne M. J. J., Kersten, Ferry F. J., Cheng, Tsing, Verdoes, Martijn, van Erp, Piet E. J., Verbeek, Sjef, Reinheckel, Thomas, Hendriks, Wiljan J. A. J., Schalkwijk, Joost, Zeeuwen, Patrick L. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602906/
https://www.ncbi.nlm.nih.gov/pubmed/28596234
http://dx.doi.org/10.1096/fj.201700267R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602906/
https://www.ncbi.nlm.nih.gov/pubmed/28596234
http://dx.doi.org/10.1096/fj.201700267R

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