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Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells

BACKGROUND: Immunotherapy is a very fast expanding field within drug discovery and, hence, rapid and inexpensive expression of antibodies would be extremely valuable. Antibodies are, however, difficult to express. Multifunctional antibodies with additional binding domains further complicate the expr...

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Detalles Bibliográficos
Autores principales: Fang, Xiaotian T., Sehlin, Dag, Lannfelt, Lars, Syvänen, Stina, Hultqvist, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603040/
https://www.ncbi.nlm.nih.gov/pubmed/28932173
http://dx.doi.org/10.1186/s12575-017-0060-7