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Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of...

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Autor principal: Derbyshire, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603098/
https://www.ncbi.nlm.nih.gov/pubmed/28951787
http://dx.doi.org/10.1155/2017/6285218
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author Derbyshire, E.
author_facet Derbyshire, E.
author_sort Derbyshire, E.
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description BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of 16 randomised controlled trials was undertaken. Trials included a total of 1,514 children and young people with ADHD who were allocated to take an omega-3/6 intervention, or a placebo. RESULTS: Of the studies identified, 13 reported favourable benefits on ADHD symptoms including improvements in hyperactivity, impulsivity, attention, visual learning, word reading, and working/short-term memory. Four studies used supplements containing a 9 : 3 : 1 ratio of eicosapentaenoic acid : docosahexaenoic acid : gamma linolenic acid which appeared effective at improving erythrocyte levels. Supplementation with this ratio of fatty acids also showed promise as an adjunctive therapy to traditional medications, lowering the dose and improving the compliance with medications such as methylphenidate. CONCLUSION: ADHD is a frequent and debilitating childhood condition. Given disparaging feelings towards psychostimulant medications, omega-3/6 fatty acids offer great promise as a suitable adjunctive therapy for ADHD.
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spelling pubmed-56030982017-09-26 Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? Derbyshire, E. J Lipids Review Article BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of 16 randomised controlled trials was undertaken. Trials included a total of 1,514 children and young people with ADHD who were allocated to take an omega-3/6 intervention, or a placebo. RESULTS: Of the studies identified, 13 reported favourable benefits on ADHD symptoms including improvements in hyperactivity, impulsivity, attention, visual learning, word reading, and working/short-term memory. Four studies used supplements containing a 9 : 3 : 1 ratio of eicosapentaenoic acid : docosahexaenoic acid : gamma linolenic acid which appeared effective at improving erythrocyte levels. Supplementation with this ratio of fatty acids also showed promise as an adjunctive therapy to traditional medications, lowering the dose and improving the compliance with medications such as methylphenidate. CONCLUSION: ADHD is a frequent and debilitating childhood condition. Given disparaging feelings towards psychostimulant medications, omega-3/6 fatty acids offer great promise as a suitable adjunctive therapy for ADHD. Hindawi 2017 2017-08-30 /pmc/articles/PMC5603098/ /pubmed/28951787 http://dx.doi.org/10.1155/2017/6285218 Text en Copyright © 2017 E. Derbyshire. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Derbyshire, E.
Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title_full Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title_fullStr Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title_full_unstemmed Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title_short Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
title_sort do omega-3/6 fatty acids have a therapeutic role in children and young people with adhd?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603098/
https://www.ncbi.nlm.nih.gov/pubmed/28951787
http://dx.doi.org/10.1155/2017/6285218
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