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Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD?
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603098/ https://www.ncbi.nlm.nih.gov/pubmed/28951787 http://dx.doi.org/10.1155/2017/6285218 |
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author | Derbyshire, E. |
author_facet | Derbyshire, E. |
author_sort | Derbyshire, E. |
collection | PubMed |
description | BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of 16 randomised controlled trials was undertaken. Trials included a total of 1,514 children and young people with ADHD who were allocated to take an omega-3/6 intervention, or a placebo. RESULTS: Of the studies identified, 13 reported favourable benefits on ADHD symptoms including improvements in hyperactivity, impulsivity, attention, visual learning, word reading, and working/short-term memory. Four studies used supplements containing a 9 : 3 : 1 ratio of eicosapentaenoic acid : docosahexaenoic acid : gamma linolenic acid which appeared effective at improving erythrocyte levels. Supplementation with this ratio of fatty acids also showed promise as an adjunctive therapy to traditional medications, lowering the dose and improving the compliance with medications such as methylphenidate. CONCLUSION: ADHD is a frequent and debilitating childhood condition. Given disparaging feelings towards psychostimulant medications, omega-3/6 fatty acids offer great promise as a suitable adjunctive therapy for ADHD. |
format | Online Article Text |
id | pubmed-5603098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-56030982017-09-26 Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? Derbyshire, E. J Lipids Review Article BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a debilitating behavioural disorder affecting daily ability to function, learn, and interact with peers. This publication assesses the role of omega-3/6 fatty acids in the treatment and management of ADHD. METHODS: A systematic review of 16 randomised controlled trials was undertaken. Trials included a total of 1,514 children and young people with ADHD who were allocated to take an omega-3/6 intervention, or a placebo. RESULTS: Of the studies identified, 13 reported favourable benefits on ADHD symptoms including improvements in hyperactivity, impulsivity, attention, visual learning, word reading, and working/short-term memory. Four studies used supplements containing a 9 : 3 : 1 ratio of eicosapentaenoic acid : docosahexaenoic acid : gamma linolenic acid which appeared effective at improving erythrocyte levels. Supplementation with this ratio of fatty acids also showed promise as an adjunctive therapy to traditional medications, lowering the dose and improving the compliance with medications such as methylphenidate. CONCLUSION: ADHD is a frequent and debilitating childhood condition. Given disparaging feelings towards psychostimulant medications, omega-3/6 fatty acids offer great promise as a suitable adjunctive therapy for ADHD. Hindawi 2017 2017-08-30 /pmc/articles/PMC5603098/ /pubmed/28951787 http://dx.doi.org/10.1155/2017/6285218 Text en Copyright © 2017 E. Derbyshire. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Derbyshire, E. Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title | Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title_full | Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title_fullStr | Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title_full_unstemmed | Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title_short | Do Omega-3/6 Fatty Acids Have a Therapeutic Role in Children and Young People with ADHD? |
title_sort | do omega-3/6 fatty acids have a therapeutic role in children and young people with adhd? |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603098/ https://www.ncbi.nlm.nih.gov/pubmed/28951787 http://dx.doi.org/10.1155/2017/6285218 |
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