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Multiple neuropathologies and dementia in the aging brain: A key role for cerebrovascular disease?

This short perspective discusses the conclusions of a Research Roundtable meeting held in October in 2014 within the overall theme of understanding the role of additional/comorbid pathologies in the aging brain and their potential interaction with clinical Alzheimer's disease and other dementia...

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Detalles Bibliográficos
Autores principales: Charidimou, Andreas, Viswanathan, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603192/
https://www.ncbi.nlm.nih.gov/pubmed/28944284
http://dx.doi.org/10.1016/j.trci.2016.11.001
Descripción
Sumario:This short perspective discusses the conclusions of a Research Roundtable meeting held in October in 2014 within the overall theme of understanding the role of additional/comorbid pathologies in the aging brain and their potential interaction with clinical Alzheimer's disease and other dementia phenotypes. We specifically examine the key role of for cerebrovascular small vessel disease in this context and highlight future directions.