Cargando…
Investigation of the inhibition effect and mechanism of myricetin to Suilysin by molecular modeling
In the present study, the inhibitory effect and mechanism of myricetin, a natural flavonoid compound, in relation to Suilysin (SLY) were investigated through molecular dynamics simulations, mutational analysis and fluorescence-quenching assays. Myricetin is a potential inhibitor that does not exhibi...
Autores principales: | Niu, Xiaodi, Sun, Lin, Wang, Guizhen, Gao, Yawen, Yang, Yanan, Wang, Xiyan, Wang, Hongsu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603505/ https://www.ncbi.nlm.nih.gov/pubmed/28924148 http://dx.doi.org/10.1038/s41598-017-12168-y |
Ejemplares similares
-
Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling
por: Wang, Guizhen, et al.
Publicado: (2018) -
Insight into the Dual Inhibition Mechanism of Corilagin
against MRSA Serine/Threonine Phosphatase (Stp1) by Molecular Modeling
por: Yang, Yanan, et al.
Publicado: (2020) -
Baicalin Weakens Staphylococcus aureus Pathogenicity by Targeting Sortase B
por: Wang, Guizhen, et al.
Publicado: (2018) -
Morin Attenuates Streptococcus suis Pathogenicity in Mice by Neutralizing Suilysin Activity
por: Li, Gen, et al.
Publicado: (2017) -
Discovery of the Novel Inhibitor Against New Delhi Metallo-β-Lactamase Based on Virtual Screening and Molecular Modelling
por: Wang, Xiyan, et al.
Publicado: (2020)