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Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires

Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predi...

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Detalles Bibliográficos
Autores principales: Conant, Genevieve, Ahadian, Samad, Zhao, Yimu, Radisic, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603510/
https://www.ncbi.nlm.nih.gov/pubmed/28924210
http://dx.doi.org/10.1038/s41598-017-12048-5

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