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Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires
Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predi...
Autores principales: | Conant, Genevieve, Ahadian, Samad, Zhao, Yimu, Radisic, Milica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603510/ https://www.ncbi.nlm.nih.gov/pubmed/28924210 http://dx.doi.org/10.1038/s41598-017-12048-5 |
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