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Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca(2+) entry in mouse pancreatic β-cells
In regulatory toxicology, the dose-response relationship is a key element towards fulfilling safety assessments and satisfying regulatory authorities. Conventionally, the larger the dose, the greater the response, following the dogma “the dose makes the poison”. Many endocrine disrupting chemicals,...
Autores principales: | Villar-Pazos, Sabrina, Martinez-Pinna, Juan, Castellano-Muñoz, Manuel, Alonso-Magdalena, Paloma, Marroqui, Laura, Quesada, Ivan, Gustafsson, Jan-Ake, Nadal, Angel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603522/ https://www.ncbi.nlm.nih.gov/pubmed/28924161 http://dx.doi.org/10.1038/s41598-017-11995-3 |
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