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A Novel Mouse Model of Traumatic Optic Neuropathy Using External Ultrasound Energy to Achieve Focal, Indirect Optic Nerve Injury
Traumatic optic neuropathy (TON) is a devastating cause of permanent visual loss following blunt injury to the head. Animal models for TON exist, but most fail to recapitulate the clinical scenario of closed head indirect trauma to the nerve and subsequent neurodegeneration. Thus, we developed a cli...
Autores principales: | Tao, Wensi, Dvoriantchikova, Galina, Tse, Brian C., Pappas, Steven, Chou, Tsung-Han, Tapia, Manuel, Porciatti, Vittorio, Ivanov, Dmitry, Tse, David T., Pelaez, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603527/ https://www.ncbi.nlm.nih.gov/pubmed/28924145 http://dx.doi.org/10.1038/s41598-017-12225-6 |
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