Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer

Nucleotide excision repair (NER) pathway plays critical roles in repairing DNA disorders caused by platinum. To comprehensively understand the association between variants of NER and clinical outcomes of platinum-based chemotherapy, 173 SNPs in 27 genes were selected to evaluate association with tox...

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Detalles Bibliográficos
Autores principales: Song, Xiao, Wang, Shiming, Hong, Xuan, Li, Xiaoying, Zhao, Xueying, Huai, Cong, Chen, Hongyan, Gao, Zhiqiang, Qian, Ji, Wang, Jiucun, Han, Baohui, Bai, Chunxue, Li, Qiang, Wu, Junjie, Lu, Daru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603542/
https://www.ncbi.nlm.nih.gov/pubmed/28924235
http://dx.doi.org/10.1038/s41598-017-08257-7

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