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Chebulinic acid inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression

Excessive migration of vascular smooth muscle cells (VSMCs) after vascular injury contributes to the development of occlusive vascular disease. Inhibition of VSMC migration is a validated therapeutic modality for occlusive vascular diseases, such as atherosclerosis and restenosis. We investigated th...

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Detalles Bibliográficos
Autores principales: Song, In-Sung, Jeong, Yu Jeong, Park, Jung-Hyun, Shim, Sungbo, Jang, Sung-Wuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603554/
https://www.ncbi.nlm.nih.gov/pubmed/28924208
http://dx.doi.org/10.1038/s41598-017-12221-w