Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1

Coronary artery anomalies may cause life-threatening cardiac complications; however, developmental mechanisms underpinning coronary artery formation remain ill-defined. Here we identify an angiogenic cell population for coronary artery formation in mice. Regulated by a DLL4/NOTCH1/VEGFA/VEGFR2 signa...

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Detalles Bibliográficos
Autores principales: Wang, Yidong, Wu, Bingruo, Lu, Pengfei, Zhang, Donghong, Wu, Brian, Varshney, Shweta, del Monte-Nieto, Gonzalo, Zhuang, Zhenwu, Charafeddine, Rabab, Kramer, Adam H., Sibinga, Nicolas E., Frangogiannis, Nikolaos G., Kitsis, Richard N., Adams, Ralf H., Alitalo, Kari, Sharp, David J., Harvey, Richard P., Stanley, Pamela, Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603578/
https://www.ncbi.nlm.nih.gov/pubmed/28924218
http://dx.doi.org/10.1038/s41467-017-00654-w

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